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Original Research 


CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY

N.B.GHIWARE, T.M. NESARI, N.Y.GOND.

Abstract
An uncontrolled, open label clinical study was done on twenty-one smear positive patients of Plasmodium vivax malaria. High solid content de-flocculated suspension of Piper nigrum and Nyctanthes arbortristis was given to patients after their enrolment in study. Vital signs and symptoms of malaria as body temperature, chilly felling/ rigors, headache, body ache, nausea/vomiting and anemia were recorded before treatment, after first and second week of treatment. Improvement in condition was recorded as shifting of gradation in signs of malaria. Decrease in increased body temperature was recorded at the end of first week of treatment (P<0.001). Global assessment suggests improvemen twith in first week of treatment from chilly felling/rigors, headache and body ache. Recovery from nausea/vomiting and anemic signs was observed only after second week of treatment.Negative smear test for Plasmodium vivax was observed at the end of treatment schedulein all patients.

Key words: Polyherbal formulation, Plasmodium vivax, Antimalarial medicine,Piper nigrum, Nyctanthes arbortristis, Medicinal plants.


 
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Pubmed Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . J Res Educ Indian Med . 0; 0(0): -.

Web Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . https://www.jreim-ayushjournal.com/?mno=191573 [Access: April 11, 2023].

AMA (American Medical Association) Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . J Res Educ Indian Med . 0; 0(0): -.


Vancouver/ICMJE Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . J Res Educ Indian Med . (0), [cited April 11, 2023]; 0(0): -.


Harvard Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND (0) CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . J Res Educ Indian Med , 0 (0), -.


Turabian Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. 0. CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . Journal of Research and Education in Indian Medicine, 0 (0), -.


Chicago Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. "CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY ." Journal of Research and Education in Indian Medicine 0 (0), -.


MLA (The Modern Language Association) Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND. "CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY ." Journal of Research and Education in Indian Medicine 0.0 (0), -. Print.


APA (American Psychological Association) Style

N.B.GHIWARE, T.M. NESARI, N.Y.GOND (0) CLINICAL VALIDATION OF Piper nigrum AND Nyctanthes arbortristis FORMULATION FOR ANTIMALARIAL ACTIVITY . Journal of Research and Education in Indian Medicine, 0 (0), -.


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