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Original Research 


DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA.

Abstract
: Portulaca oleracea Linn. (Family: Portulaceae) is a creeping annual herb, native of tropical and subtropical region. It has been used since long time as domestic remedy by ancient Unani and Ayurvedic physicians. Petroleum ether extract of its whole plant collected by soxhlet apparatus were studied for diuretic activity in Albino rats. It was compared with placebo and standard control groups treated with carboxylmethyl cellulose (CMC) and furosemide respectively. Three parameters were taken to assess the diuretic activity i.e. (1) Urine output (2) Reduction in body weight and (3) Electrolytes (sodium, potassium and chloride) concentration in urine excreted. The animals of test group, which received 90 mg/kg extract of Khurfa whole plant showed urine output equal to the animals of standard group. It was also observed that by increasing the dose of test drug, urine excretion was increased. Weight reductions were noticed in all groups and were related to volume of urine output. The group of animals that passed more urine lost more body weight. Urine ion concentration of sodium and potassium were lowest in standard group whereas in test groups as the dose were increased concentration of sodium and potassium excretion also increased in urine.

Key words: Portulaca oleracea Linn., Petroleum ether extract, Diuretic, Furosemide, Metabolic cage, Flame photometer.


 
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Pubmed Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. J Res Educ Indian Med . 2010; 16(3-4): 85-88.

Web Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. https://www.jreim-ayushjournal.com/?mno=192182 [Access: December 06, 2023].

AMA (American Medical Association) Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. J Res Educ Indian Med . 2010; 16(3-4): 85-88.


Vancouver/ICMJE Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. J Res Educ Indian Med . (2010), [cited December 06, 2023]; 16(3-4): 85-88.


Harvard Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA (2010) DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. J Res Educ Indian Med , 16 (3-4), 85-88.


Turabian Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. 2010. DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. Journal of Research and Education in Indian Medicine, 16 (3-4), 85-88.


Chicago Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. "DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS." Journal of Research and Education in Indian Medicine 16 (2010), 85-88.


MLA (The Modern Language Association) Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA. "DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS." Journal of Research and Education in Indian Medicine 16.3-4 (2010), 85-88. Print.


APA (American Psychological Association) Style

KHALEEQ UR RAHMAN, SHAFEEQ UR RAHMAN, ARSHIYA SULTANA (2010) DIURETIC ACTIVITY OF PORTULACA OLERACEA LINN. (KHURFA) IN EXPERIMENTAL ANIMALS. Journal of Research and Education in Indian Medicine, 16 (3-4), 85-88.


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